Abstract | Road infrastructure (RI) resilience is significant for the prosperity and development of modern societies. Lightweight steel structures, such as sign bridges, constitute an integral part of modern highways and their proper design ensures the safety of the RI users. Sign support structures provide direction instructions and/or traffic information to the drivers and their spans become constantly longer due to lane number increase. A common characteristic of such structures is the large dimensions of signpost plates, compared to the surfaces of the structural members, resulting in a critical role of wind loading in structural design. Moreover, such structures are exposed to harsh environmental conditions, thus being prone to corrosion, attacking the metal surface, creating a rust film, progressively reducing the material thickness, consequently producing a decrease in the structural performance in terms of strength, stiffness, and ductility. Moreover, corrosion accelerates fatigue effects and reduces the remaining lifetime of the connections and hence of the entire structure. In the present work the effect of corrosion on the fatigue resistance of typical sign bridges is quantified. Towards that objective, a methodology to assess the remaining lifetime is developed and applied to typical sign bridge structures of contemporary motorways with different shapes.