Abstract | Total knee arthroplasty has become quite widespread, especially among patients of 70+ years. Unfortunately, failure of this surgery is not so uncommon. As a result, a revision surgery is sometimes needed, resulting in a great ordeal for patients. One of the major causes of this failure is the aseptic loosening of either the tibial or the femoral component, with that of the tibial component being more common. Our goal is to evaluate the performance of metallic knee implants used in total knee arthroplasty. More specifically, the aim is to identify critical areas of failure and the prevalent failure mechanisms due to fatigue. A probabilistic analysis will follow, in order to calculate the probability of failure as a function of walking cycles and loads on the knee joint.In the end, it will become possible to predict the likelihood of implant failure in the course of a patient’s lifetime. It will also be possible to determine the probability of failure depending on the patient’s habits and, as a result, how much the patient is allowed to stress the joint after the surgery depending on his/her weight. Similarly, the calculations will offer decision support on how much, if any, weight he/she should lose in order to lessen the probability of failure to an acceptable level. Ultimately, rehabilitation becomes more patient-specific and, therefore, likely much easier and less time-consuming.