Abstract | Presented herein is a methodology for the seismic assessment of the reliability of urban water distribution networks (UWDN) based on general seismic assessment standards, as per the American Lifelines Alliance (ALA) guidelines, and localized historical records of critical risk-of-failure metrics pertaining to the specific UWDN under assessment. The proposed methodology is applicable to UWDN under both normal or abnormal operating conditions (such as intermittent water supply), and the assessment of reliability incorporates data of past non-seismic damage, the vulnerabilities of the network components against seismic loading, and the topology of a UWDN. Historical data obtained using records of pipe burst incidents are processed to produce clustered ‘survival curves’, depicting the pipes’ estimated survival rate over time. The survival curves are then used to localize the generalized fragility values of the network components (primarily pipes), as assessed using the approach suggested by the ALA guidelines. The network reliability is subsequently assessed using Graph Theory (Djikstra’s shortest path algorithm), while the system reliability is calculated using Monte Carlo simulation. The methodology proposed is demonstrated on a simple small-scale network and on a real-scale district metered area (DMA). The proposed approach allows the estimation of the probability that a network fails to provide the desired level of service and allows for the prioritization of retrofit interventions and of capacity-upgrade actions pertaining to existing water pipe networks.