Abstract | The building and structure related part of the Euratom funded Project METIS (metis-h2020.eu) is focused on the evaluation of fragility curves, giving failure probabilities for increasing ground motion intensity, intensity measure selection, uncertainty quantification and bayesian updating of fragility curves. While METIS improves the methodologies for the seismic assessment of NPPs, work package 6 (WP) focuses on the structural part of the project delivering the methodologies for specific, detailed fragility curves and applying these to the case study. The work will finalize in guidelines for the application of the developed methodologies. In the following, first work within the fragility analysis part of the project and future topics will be presented.